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Total Synthesis of Pumiliotoxins A and 225F

✍ Scribed by Hirashima, Shintaro; Aoyagi, Sakae; Kibayashi, Chihiro

Book ID: 126249216
Publisher: American Chemical Society
Year: 1999
Tongue: English
Weight: 116 KB
Volume: 121
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja991918x

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📜 SIMILAR VOLUMES

ChemInform Abstract: Total Synthesis of

ChemInform Abstract: Total Synthesis of Pumiliotoxins A (I) and 225F (II)

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Convergent Approach to Pumiliotoxin Alka

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Enantioselective total synthesis of (+)-

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The convergent total synthesis of pumiliotoxins by attachment of the side chain to a suitably functionalized core indolizidinone derivative has been achieved. The use of an aldoltype addition condensation strategy, intended to provide for the stereoselective generation of the exocyclic double bond,