Total synthesis of myriocin
โ
Kee-Young Lee; Chang-Young Oh; Yong-Hyun Kim; Jae-Eun Joo; Won-Hun Ham
๐
Article
๐
2002
๐
Elsevier Science
๐
French
โ 211 KB
A concise, stereocontrolled synthesis of myriocin was achieved. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0), MgBr 2 -promoted allylic stannane addition, and palladium(0)-catalyzed coupling of a vinyl iodide with an organozinc reagent.