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Stereoselective total synthesis of (+)-myriocin from d-mannose

โœ Scribed by Oishi, Takeshi; Ando, Koji; Chida, Noritaka


Book ID
120395213
Publisher
Royal Society of Chemistry
Year
2001
Tongue
English
Weight
80 KB
Volume
19
Category
Article
ISSN
1359-7345

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A concise, stereocontrolled synthesis of myriocin was achieved. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0), MgBr 2 -promoted allylic stannane addition, and palladium(0)-catalyzed coupling of a vinyl iodide with an organozinc reagent.

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