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Total synthesis of methyl 14-hydroxy-(all-cis)-5,8,11-tetradecatrienoate: A useful intermediate for the synthesis of arachidonic acid analogues

โœ Scribed by Luning Han; Raj K. Razdan


Book ID
108386421
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
169 KB
Volume
39
Category
Article
ISSN
0040-4039

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An efficient and simple total synthesis of the two C(8) diastereomers of 2, of interest as possible hormonal releasing agents, is described. A previous publication from this laboratory has described the synthesis of the two diastereomeric lo-hydroxy-11, lZ(S, S)-epoxyeicosa-5,9,14(Z)-trienoic acids