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Total Synthesis of (+)-Cryptocaryalactone and of a Diastereoisomer of (+)-Strictifolione via Ring-Closing Metathesis (RCM) and Olefin Cross-Metathesis (CM)

✍ Scribed by Gowravaram Sabitha; Bhaskar Vangala; S. Siva Sankara Reddy; Jhillu S. Yadav

Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
217 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Ring‐closing metathesis (RCM) and olefin cross‐metathesis (CM) reactions were used as the key steps for the synthesis of (+)‐cryptocaryalactone (1) and the first synthesis of the diastereoisomer 3 of (+)‐strictifolione, starting from the commercially available L‐malic acid (=(2__S__)‐2‐hydroxybutanedioic acid).

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