Blasticidin S is an antibiotic produced by Streotomyces -gi\_seochromogene\_s\_' and the structure has been established as shown in FIG. 1: It consists of a pyrimidine nucleoside and P-amino acid named cytosinine and blastidic acid, respectively. Hitherto, several reports had been published on the
Total Synthesis of (+)-Blasticidin S
β Scribed by Yoshiyasu Ichikawa; Keiko Hirata; Masayoshi Ohbayashi; Minoru Isobe
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 286 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0947-6539
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π SIMILAR VOLUMES
In the works on the chemistry of blasticidln S (I), a methabollte.of Streotomyces griseochromogenes, we have demonstrated its unique structural feature which consists of a new nucleoslde cytosinine (II) ana a new amino acid, blastiaic 1-4 acid (III) on the basis of chemical reactions and spectral ev
Blasticidin S-resistant mutants of S. cerevisiae were isolated and characterized. Resistant mutations were found to fall into two complementation groups. A single recessive nuclear gene was responsible for each group, donated as blsl and bls2, respectively. A gene blsl was linked to an ilv3 gene loc