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Total synthesis of aspirin-triggered 15-epi-lipoxin A4
✍ Scribed by Ana R Rodrı́guez; Bernd W Spur
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 95 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure a-hydroxy and a$-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material. Connection by a six carbons unit uses Wittig-type reactions notably involving a stabilized arsonium yl
The first total synthesis of ent-15(RS)-2,3-dinor-5,6-dihydro-8-epi-PGF2c~ 1 is described using diacetone-D-glucose as starting material. The major urinary metabolite of the isoprostane 8-epi-PGF2ct is 2,3-dinor-5,6-dihydro-8-epi-PGF2c~, which is a potent lipid peroxidation index to obtain an integr