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Total synthesis of (+)-aplasmomycin

โœ Scribed by White, James D.; Vedananda, Thalathani R.; Kang, Myung Chol.; Choudhry, Satish C.


Book ID
126234550
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
370 KB
Volume
108
Category
Article
ISSN
0002-7863

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Stereospecific synthesis of the C(3)-C(1
โœ James D. White; Shen-chun Kuo; Thalathani R. Vedananda ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 171 KB

## Sumnary: A key subunit of aplasmomycin comprising C3-Cl0 of the syrnnetrical macrodiolide structure has been synthesized in optically pure form by two routes from (RI-(+I-pulegone. A strategic intermediate in our recent total synthesis of aplasmomycin (111 was the S-lactone 2, which provided th