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Total synthesis of (.+-.)-acorone

โœ Scribed by McCrae, D. A.; Dolby, Lloyd


Book ID
127114333
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
566 KB
Volume
42
Category
Article
ISSN
0022-3263

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A new strategy for the construction of spiro [4,5]decanes is described and involves a bridgehead substitution of a methoxyl group in 6 by a methyl group, followed by an oxidative cleavage resulting in a stereogenic spirocentre which culminated in the formal synthesis of acorone.