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Total synthesis of 1.alpha.,25(R)-dihydroxy vitamin D3 26, 23(S)-lactone (calcitriol lactone), a natural metabolite of vitamin D3

โœ Scribed by Wovkulich, Peter M.; Baggiolini, Enrico G.; Hennessy, Bernard M.; Uskokovic, Milan R.; Mayer, Eberhard; Norman, Anthony W.


Book ID
126145716
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
544 KB
Volume
48
Category
Article
ISSN
0022-3263

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Stereoselective synthesis of (25R)-25,26
โœ Sachiko Yamada; Keiko Nakayama; Hiroaki Takayama; Toshimasa Shinki; Tatsuo Suda ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 256 KB

25l?)-25,26-Dihydroxy-23-oxovitamin D3 was synthesized efficiently and stereoselectively, and it was converted enzymatically to (25R\_)-lcr,25,26-trihydroxy-23-oxovitamin D3, a putative metabolite of la,25\_dihydroxyvitamin D3. The spectral and chemical properties of (25R&25,26-dihydroxy-23-oxovitam