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Total synthesis of 1-deoxy-7,8a-di-epi-castanospermine and formal synthesis of pumiliotoxin-251D

✍ Scribed by Sultane, Prakash R.; Mohite, Amar R.; Bhat, Ramakrishna G.


Book ID
123454441
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
532 KB
Volume
53
Category
Article
ISSN
0040-4039

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A new and efficient enantioselective total synthesis of the title deoxycastanospermine derivative has been developed, based on amino acid and b-ketophosphonate chemistry, as well as employment of internal asymmetric induction for the creation of the new chiral centers proved successful. With proper