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Total Syntheses of All Four Isomers of cis-1,2-Dihydroxypyrrolizidine

โœ Scribed by Casiraghi, Giovanni; Spanu, Pietro; Rassu, Gloria; Pinna, Luigi; Ulgheri, Fausta


Book ID
126130573
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
539 KB
Volume
59
Category
Article
ISSN
0022-3263

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All four isomers of the spermine alkaloid kukoamine were unambiguously prepared through diacylation with O,O'-dibenzylcaffeyl chloride of suitably protected (benzyl and/or trityl groups) spermine derivatives, assembled on solid and/or in liquid phase using 1%alanine and y-aminobutyric acid, followed