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Total Solid-Phase Synthesis of the Azathiocoraline Class of Symmetric Bicyclic Peptides

✍ Scribed by Núria Bayó-Puxan; Ariadna Fernández; Judit Tulla-Puche; Estela Riego; Carmen Cuevas; Mercedes Álvarez; Fernando Albericio


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
423 KB
Volume
12
Category
Article
ISSN
0947-6539

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✍ Cesare Gennari; Antonia Mielgo; Donatella Potenza; Carlo Scolastico; Umberto Pia 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 2 views

The solid-phase synthesis and characterization of a series of accomplished by means of diisopropylcarbodiimide (DIC)/ hydroxyazabenzotriazole (HOAt). Coupling between amino peptides (4-15) containing reverse-turn mimetic bicyclic lactams is reported. The bicyclic lactams (1a, 1b) possess acids and t