๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Topoisomerase I in multiple drug resistance

โœ Scribed by Augusto Pessina


Book ID
104922290
Publisher
Springer
Year
1993
Tongue
English
Weight
783 KB
Volume
12
Category
Article
ISSN
0920-9069

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Multiple drug resistance
โœ Lester A. Mitscher; Segaran P. Pillai; Elmer J. Gentry; Delbert M. Shankel ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 348 KB

Multiple drug resistance to antibacterial agents, antifungals, antivirals, antiprotozoals, and antitumor agents has risen spectacularly in the last decade or so and presently threatens eventually to put an end to successful chemotherapy in all of the above fields. This review summarizes the known or

Drug resistance: Multiple opponents
โœ McCarthy, Nicola ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 180 KB
Topoisomerase I interactive drugs in chi
โœ Clinton F. Stewart; William C. Zamboni; William R. Crom; Amar Gajjar; Richard L. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer US ๐ŸŒ English โš– 939 KB

Topotecan, irinotecan, and 9-aminocamptothecin (9-AC) are analogs of the plant alkaloid 20(S)-camptothecin (CMT), the prototypical DNA topoisomerase I interactive agent. These agents interact with the topoisomerase I-DNA complex and prevent resealing topoisomerase I-mediated DNA single-strand breaks