Multiple drug resistance
β Scribed by Lester A. Mitscher; Segaran P. Pillai; Elmer J. Gentry; Delbert M. Shankel
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 348 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0198-6325
No coin nor oath required. For personal study only.
β¦ Synopsis
Multiple drug resistance to antibacterial agents, antifungals, antivirals, antiprotozoals, and antitumor agents has risen spectacularly in the last decade or so and presently threatens eventually to put an end to successful chemotherapy in all of the above fields. This review summarizes the known origins of the problem, its present dimensions, the means employed to combat the phenomenon and promising avenues for future developments.
π SIMILAR VOLUMES
Reviews is pleased to provide an outlet for the publication of selected articles representing the invited lectures presented at the 3rd Winter Conference on Medicinal and Bioorganic Chemistry, January 23-29, 1999. This particular group of articles addresses various aspects of the multiple drug resis
## Abstract Induction of Pβglycoproteinβrelated multiβdrugβresistance (MDR) has been shown innormal and malignant tissues to result from environmental stresses such as heat shock, exposure to carcinogens or Xβray irradiation. To identify conditions under which MDR is enhanced during antiβneoplastic