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Toll-like receptor signaling in liver regeneration, fibrosis and carcinogenesis

✍ Scribed by Ekihiro Seki; EekJoong Park; Jiro Fujimoto

Book ID
118088426
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
732 KB
Volume
41
Category
Article
ISSN
1386-6346

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Toll-like receptors (TLRs) act as innate immune signal sensors and play central roles in host defense. Myeloid differentiation factor (MyD) 88 is a common adaptor molecule required for signaling mediated by TLRs. When the receptors are activated, cells bearing TLRs produce various proinflammatory cy