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Toll-Like Receptor Signaling in the Liver

✍ Scribed by Robert F. Schwabe; Ekihiro Seki; David A. Brenner

Book ID
119759084
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
723 KB
Volume
130
Category
Article
ISSN
0016-5085

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Absence of toll-like receptor 4 (TLR4) signaling in the donor organ reduces ischemia and reperfusion injury in a murine liver transplantation model
✍ Xiu-Da Shen; Bibo Ke; Yuan Zhai; Feng Gao; Sei-Ichiro Tsuchihashi; Charles R. La πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 679 KB

This study analyzes how toll-like receptor 4 (TLR4) signaling in the donor organ affects the ischemia and reperfusion injury (IRI) sequel following liver transplantation. Isogenic orthotopic liver transplantations (OLTs) with rearterialization were performed in groups of wild-type (WT) and TLR4 knoc