Toll-like receptors in acute liver injury and regeneration
β Scribed by Yongyan Chen; Rui Sun
- Book ID
- 116576914
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 244 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1567-5769
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π SIMILAR VOLUMES
## Abstract __Introduction__: Sterile tissue injury induces an inflammatory response involving cytokines that have crucial roles in the tissue repair that follows. __Methods__: MyH3 and type 1 interferon (IFN) were assessed by qPCR after cardiotoxin (CTX)βinduced muscle injury. __Results__: CTXβind
Hepatocyte death results in a sterile inflammatory response that amplifies the initial insult and increases overall tissue injury. One important example of this type of injury is acetaminopheninduced liver injury, in which the initial toxic injury is followed by innate immune activation. Using mice