To T or not to T: reassessing the common lymphoid progenitor
β Scribed by Montecino-Rodriguez, Encarnacion; Dorshkind, Kenneth
- Book ID
- 109921038
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 285 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1529-2908
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Recent studies have begun to unravel some of the molecular pathways that appear to control the processes of T cell determination in the earliest thymocyte precursors. In addition, the analyses of mouse mutants with an entirely alymphoid thymus have shed light on the developmental relationship of pro
T lineage progenitors: the earliest steps en route to T lymphocytes ## Li Wu T lymphocyte development in the thymus is a tightly regulated stepwise process. The identification and characterization of the earliest T lineage progenitors and their downstream progeny now enables the study of important