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To be or not to be a pro-T?

✍ Scribed by James P Di Santo; Freddy Radtke; Hans-Reimer Rodewald


Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
106 KB
Volume
12
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

✦ Synopsis


Recent studies have begun to unravel some of the molecular pathways that appear to control the processes of T cell determination in the earliest thymocyte precursors. In addition, the analyses of mouse mutants with an entirely alymphoid thymus have shed light on the developmental relationship of pro-T cells and thymic dendritic cells, revealing that development of thymocytes and thymic dendritic cells can be dissociated.


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