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To be, or not to be: NF-κB is the answer – role of Rel/NF-κB in the regulation of apoptosis

✍ Scribed by Kucharczak, Jérôme; Simmons, Matthew J; Fan, Yongjun; Gélinas, Céline

Book ID
110068311
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
368 KB
Volume
22
Category
Article
ISSN
0950-9232

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The activation of B and T cells by a wide range of stimuli can rapidly induce specific gene expression via a mechanism that promotes the nuclear translocation of different Rel/nuclear factor-kappa B (NF-kappa B) transcription factors which are normally resident in the cytoplasm. Recent findings high