The function of multiple IκB : NF-κB complexes in the resistance of cancer cells to Taxol-induced apoptosis
✍ Scribed by Dong, Qiang G; Sclabas, Guido M; Fujioka, Shuichi; Schmidt, Christian; Peng, Bailu; Wu, TianAi; Tsao, Ming-Sound; Evans, Douglas B; Abbruzzese, James L; McDonnell, Timothy J
- Book ID
- 110067003
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 349 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Multiple myeloma (MM) is a fatal lymphoid malignancy that is incurable with conventional modalities of chemotherapy. Strong and constitutive activation of nuclear factor kappa B (NF-kappaB) is a common characteristic of MM cells. In our study we successfully target NF-kappaB with a novel NF-kappaB i
## Abstract Ambiguous roles of genotoxic anticancer therapeutic‐induced NF‐κB activation in regulating gene expression (activation or suppression) and apoptosis (anti‐ or pro‐apoptosis) have recently been suggested. In order to clarify this controversy and determine the usefulness of NF‐κB blockage