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TNFα Elicits Association of PI 3-Kinase with the p60TNFR and Activation of PI 3-Kinase in Adherent Neutrophils

✍ Scribed by Helen M. Korchak; Laurie E. Kilpatrick

Book ID
115587492
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
134 KB
Volume
281
Category
Article
ISSN
0006-291X

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## Abstract In bone, a large proportion of osteoblasts, the cells responsible for deposition of new bone, normally undergo programmed cell death (apoptosis). Because mechanical loading of bone increases the rate of new bone formation, we hypothesized that mechanical stimulation of osteoblasts might