The antiapoptotic effect of guanosine is
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Patrizia Di Iorio; Patrizia Ballerini; Ugo Traversa; Ferdinando Nicoletti; Iolan
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Article
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2004
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John Wiley and Sons
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English
⚖ 309 KB
👁 1 views
## Abstract Guanosine has many trophic effects in the CNS, including the stimulation of neurotrophic factor synthesis and release by astrocytes, which protect neurons against excitotoxic death. Therefore, we questioned whether guanosine protected astrocytes against apoptosis induced by staurosporin