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Activation of eNOS in rat portal hypertensive gastric mucosa is mediated by TNF-α via the PI 3-kinase–Akt signaling pathway

✍ Scribed by Hirofumi Kawanaka; Michael K. Jones; Imre L. Szabo; Dolgor Baatar; Rama Pai; Kouji Tsugawa; Keizo Sugimachi; I.James Sarfeh; Andrzej S. Tarnawski


Book ID
111721733
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
557 KB
Volume
35
Category
Article
ISSN
0270-9139

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The antiapoptotic effect of guanosine is
✍ Patrizia Di Iorio; Patrizia Ballerini; Ugo Traversa; Ferdinando Nicoletti; Iolan 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 309 KB 👁 1 views

## Abstract Guanosine has many trophic effects in the CNS, including the stimulation of neurotrophic factor synthesis and release by astrocytes, which protect neurons against excitotoxic death. Therefore, we questioned whether guanosine protected astrocytes against apoptosis induced by staurosporin