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Titanium tetrachloride promoted reaction of silyl ketene acetals with epoxides: a new method for the synthesis of γ-butanolides

✍ Scribed by Veselin Maslak; Radomir Matović; Radomir N. Saičić

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
65 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new method for the synthesis of g-butanolides is described. The titanium tetrachloride promoted reaction of silyl ketene acetals with epoxides, followed by acidic work-up, affords the corresponding butyrolactones in 44-83% yield.

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