𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Titanium-induced cyclization of keto esters: a new method of cycloalkanone synthesis

✍ Scribed by McMurry, John E.; Miller, Dennis D.

Book ID
111916595
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
290 KB
Volume
105
Category
Article
ISSN
0002-7863

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of isocaryophyllene by titaniu
Synthesis of isocaryophyllene by titanium-induced keto ester cyclization.
✍ John E. Mc Murry; Dennis D. Miller 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 187 KB

A total synthesis of d,l isocaryophyllene is reported that employs the titanium-induced cyclization of a keto ester as the key step in forming the cyclononenone ring. The synthesis requires four steps starting from ethyl geranylacetate, and the key cyclization occurs in 38% yield.

A Facile Total Synthesis of (±)-Acorager
A Facile Total Synthesis of (±)-Acoragermacrone by Titanium-Induced Keto Ester Cyclization
✍ Weidong Li; Ying Li; Yulin Li 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 143 KB

## Abstract (±)‐Acoragermacrone, a natural occurring germacrane‐type sesquiterpenoid, was synthesized from geranyl acetate via eight steps by employing titanium‐induced intramolecular keto α,β‐unsaturated ester coupling as key step.