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Titanium-mediated cyclizations of .beta.-keto esters with acetals: a convenient route to 2-carbalkoxycycloalkenones

✍ Scribed by Funk, Raymond L.; Fitzgerald, John F.; Olmstead, Thomas A.; Para, Kim S.; Wos, John A.


Book ID
126989757
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
252 KB
Volume
115
Category
Article
ISSN
0002-7863

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## Abstract Benzyne and its 3,4,5,6‐tetraphenyl, 3‐ and 4‐methyl, 3‐methoxy and 4,5‐difluoro derivatives react with acetic acid 2‐selenoxo‐2__H__‐pyridin‐1‐yl esters 4a‐e to give benzo[__b__]seleno[2,3‐__b__]pyridines 10–15 in modest yields. The benzynes were generated by one or more of the followi