Debrisoquine oxidation polymorphism in a
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M. E. Veronese; S. McLean
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Article
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1991
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Springer
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English
β 389 KB
The debrisoquine hydroxylation phenotype was studied in 152 unselected healthy Tasmanian subjects, who were mostly Caucasians of British ancestry. Following a 10 mg oral dose of debrisoquine (D), the ratio of D/4-hydroxydebrisoquine excreted in 8-h urine (metabolic ratio, MR) was determined. MR valu