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Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells

✍ Scribed by Feng Wang; Lagen Wan; Caicheng Zhang; Xiaofeng Zheng; Junming Li; Zhonghua Klaus Chen

Book ID
116569363
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
388 KB
Volume
214
Category
Article
ISSN
0171-2985

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a