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Antigen-Specific Suppression by Induced CD4+CD25high Regulatory T Cells in Kidney Recipients

✍ Scribed by Z. Wang; X.-Y. Fu; B.-Y. Shi; Y.-Y. Qian; L. Xiao; H.-W. Bai

Book ID: 116935083
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 496 KB
Volume: 41
Category: Article
ISSN: 0041-1345
DOI: 10.1016/j.transproceed.2009.01.093

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a