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HCV-infected hepatocytes drive CD4 + CD25 + Foxp3 + regulatory T-cell development through the Tim-3/Gal-9 pathway

✍ Scribed by Ji, Xiao J.; Ma, Cheng J.; Wang, Jia M.; Wu, Xiao Y.; Niki, Toshiro; Hirashima, Mitsumi; Moorman, Jonathan P.; Yao, Zhi Q.

Book ID
120823604
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
846 KB
Volume
43
Category
Article
ISSN
0014-2980

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## Abstract Regulatory T cells (Treg cells) have been well documented to have a crucial physiological role in preventing the development of autoimmune diseases and keeping self‐tolerance. Foxp3, a recently identified member of the forkhead transcription factors, serves as a master regulator for the