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CD4+ CD25− FoxP3+ regulatory cells are the predominant responding regulatory T cells after human rotavirus infection or vaccination in gnotobiotic pigs

✍ Scribed by Ke Wen; Guohua Li; Xingdong Yang; Tammy Bui; Muqun Bai; Fangning Liu; Jacob Kocher; Lijuan Yuan


Book ID
117947198
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
404 KB
Volume
137
Category
Article
ISSN
0019-2805

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Analysis of FOXP3 protein expression in
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The transcription factor FOXP3 plays a key role in CD4 + CD25 + regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4 + CD25 + cells that express FOXP3 protein