Ti(IV) promoted 1, 3-dipolar cycloaddition of nitrones to vinyl ethers

✍ Scribed by Pau Bayo´n; Pedro de March; Marta Figueredo; Josep Font

• Book ID: 104208977
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 669 KB
• Volume: 54
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(98)00983-1

✦ Synopsis

The 1,3-dipolar cycloaddition of nitrones to vinyl ethers is accelerated by Ti(IV) species. The efficiency of the catalyst parallels its complexation capacity. The use of Ti(iprO)2Cl 2 favours the formation of trans cycloadducts, presumably through an endo bidentate complex, in which the metal atom is simultaneously coordinated to the vinyl ether and to the cyclic nitrone or the Z isomer of the acyclic nitrones.