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1,3-Dipolar cycloaddition reactions of nitrones with alkyl vinyl ethers catalyzed by chiral oxazaborolidines

โœ Scribed by Jean-Paul G. Seerden; Mike M.M. Boeren; Hans W. Scheeren


Book ID
108378711
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
564 KB
Volume
53
Category
Article
ISSN
0040-4020

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Asymmetric 13-dipolar cycloaddition of n
โœ Jean-Paul G. Seerden; Anita W.A. Schotte op Reimer; Hans W. Scheeren ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 357 KB

## Asymmetric 1.3-dipolar cycioad@ion of n&ones with ketenc acetals is strongly catalyzed by chiral oxazaborolidines d&ived from N-tosyl-L-a-amino acids. The 5,5dialkoxyisoxuzolidines are obtained regioselectively in high yield wish high stereoselectivity and moderate enantioselectivity up to 62% ee