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Tiazofurin enhances the anabolism and toxicity of 5-fluorouracil

✍ Scribed by Richard L. Cysyk; Christine A. Chisena; Roosevelt Hyman; Anne Monks


Book ID
117468341
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
627 KB
Volume
109
Category
Article
ISSN
0304-3835

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Cultures of human colon carcinoma, HCT-8, were treated with millimolar concentrations of thymidine by different schedules designed to cytokinetically and biochemically modulate methotrexate (MTX) and 5-fluorouracil (FUra) toxicity. Thymidine (dThd)-synchronized HCT-8 cells monitored by flow cytofluo