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Hyperthermia enhances the in vitro activity of 1-hexylcarbamoyl-5-fluorouracil compared to that of 5-fluorouracil

✍ Scribed by Kusumoto, Tetsuya; Maehara, Yoshihiko; Sakaguchi, Yoshihisa; Sugimachi, Keizo

Book ID: 122530604
Publisher: Elsevier Science
Year: 1989
Weight: 488 KB
Volume: 25
Category: Article
ISSN: 0277-5379
DOI: 10.1016/0277-5379(89)90260-5

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## Abstract The authors reported in a previous study that NK012, a 7‐ethyl‐10‐hydroxy‐camptothecin (SN‐38)‐releasing nano‐system, exhibited high antitumor activity against human colorectal cancer xenografts. This study was conducted to investigate the advantages of NK012 over irinotecan hydrochlori