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Tianeptine and its main metabolite. Disposition in chronic renal failure and haemodialysis

✍ Scribed by C. Salvadori; H. Merdjan; R. Brouard; A. Baumelou; G. Nicot; D. Friès


Book ID
115273773
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
447 KB
Volume
4
Category
Article
ISSN
0767-3981

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The pharmacokinetics of 20 mg torasemide i.v. has been studied in 7 healthy controls and 9 patients with varying degrees of renal impairment. Torasemide had a t1/2 of about 4h which was independent of kidney function, as the nonrenal clearance of torasemide was 3-times greater than its renal clearan