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Threo- and erythro-β-hydroxy-L-asparagines

✍ Scribed by A. Singerman; Y. Liwschitz

Book ID: 104215628
Publisher: Elsevier Science
Year: 1968
Tongue: French
Weight: 81 KB
Volume: 9
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)75943-0

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✦ Synopsis

The recent findings of Campbell et al. (I) regarding the action of L-asparaginase on various asparagine-requiring tumours have prompted the syntheses and investigation of analogues of this amino acid (2).

We wish to report the preparation of the F-amides of three-and erythr@-~-hydroxy-L-aspartic acids by ammonolysis of O-benzyl threo-O-hydroxy-L-aspartate

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