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Three New Regions on Chromosome 17p13.3 Distal to p53 with Possible Tumor Suppressor Gene Involvement in Lung Cancer

✍ Scribed by Tsuchiya, Eiju ;Tanigami, Akira ;Ishikawa, Yuichi ;Nishida, Kazunori ;Hayashi, Moriaki ;Tokuchi, Yoshio ;Hashimoto, Takehisa ;Okumura, Sakae ;Tsuchiya, Shigehiro ;Nakagawa, Ken


Book ID
108581924
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
311 KB
Volume
91
Category
Article
ISSN
0910-5050

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Chromosome 17p is among the most frequently deleted regions in a variety of human malignancies including breast cancer. This study has further refined the localization of a putative tumour suppressor gene (TSG) at 17p13 distal to the TP53 gene in breast carcinomas. It was found that 73% (37 of 51) o