Detailed deletion mapping suggests the involvement of a tumor suppressor gene at 17p13.3, distal to p53, in the pathogenesis of lung cancers
β Scribed by Konishi, Hiroyuki; Takahashi, Takao; Kozaki, Ken-ichi; Yatabe, Yasushi; Mitsudomi, Tetsuya; Fujii, Yoshitaka; Sugiura, Takahiko; Matsuda, Hikaru; Takahashi, Toshitada; Takahashi, Takashi
- Book ID
- 110061606
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 431 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The short arm of chromosome 1 is among the most frequently affected regions in various types of common adult cancers as well as in neuroblastoma. In a previous study of ours, frequent allelic imbalance at the TP73 locus at 1p36 was noted in lung cancer despite the absence of TP73 mutations. This sug
Chromosome 17p is among the most frequently deleted regions in a variety of human malignancies including breast cancer. This study has further refined the localization of a putative tumour suppressor gene (TSG) at 17p13 distal to the TP53 gene in breast carcinomas. It was found that 73% (37 of 51) o