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Three-dimensional heteronuclear NMR studies of RNA

✍ Scribed by Nikonowicz, Edward P.; Pardi, Arthur

Book ID
109779307
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
354 KB
Volume
355
Category
Article
ISSN
0028-0836

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The novel application of 2D heteronuclear NMR experiments to a single-stranded RNA fragment 5'-GCAU\*GGCU\*ACU\*U\*-3' labelled with 5-fluorouridine (U\*) at four sites is reported. Heteronuclear equivalents of COSY and NOESY experiments are described, both implemented in the phase-sensitive mode. T