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Three-dimensional contrast-enhanced steady-state free precession for improved catheter-directed coronary magnetic resonance angiography

✍ Scribed by Jordin D. Green; Reed A. Omary; Brian E. Schirf; Richard Tang; James C. Carr; Debiao Li

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
195 KB
Volume
22
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Purpose

To demonstrate the feasibility of three‐dimensional thick‐partition, contrast‐enhanced, catheter‐directed coronary artery magnetic resonance angiography (MRA) and test the hypothesis that three‐dimensional imaging improves coronary artery background contrast‐to‐noise ratio (CNR) compared to two‐dimensional imaging.

Materials and Methods

Catheters were advanced into the coronary arteries of swine (N = 6) under MR guidance. Three‐dimensional coronary MRA was performed after intracoronary injection of a small dose of contrast media using magnetization‐prepared steady‐state free precession (SSFP) with two thick partitions. For comparison, two magnetization‐prepared two‐dimensional SSFP scans were also performed, one with no signal averaging and one with two signal averages. All sequences had the same coverage and in‐plane spatial resolution.

Results

The coronary artery was successfully catheterized in all (6/6) animals. CNR for three‐dimensional imaging was 11.1 ± 1.2 for proximal arterial segments and 4.3 ± 0.4 for distal segments. Without averaging, two‐dimensional imaging CNRs for proximal and distal segments were 5.0 ± 0.7 and 1.2 ± 0.2, respectively. With averaging, two‐dimensional imaging CNRs for proximal and distal segments were 9.4 ± 1.5 and 2.9 ± 0.4, respectively. Three‐dimensional imaging showed a statistically significant increase in CNR over all two‐dimensional imaging for both proximal and distal segments (P < 0.05).

Conclusion

Three‐dimensional thick‐partition, contrast‐enhanced, catheter‐directed coronary MRA is feasible and improves CNR over two‐dimensional projection imaging. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.

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