Three-component one-pot synthesis of fun
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Stéphane Azoulay; Nuno Monteiro; Geneviève Balme
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Article
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2002
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Elsevier Science
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French
β 313 KB
A three-component synthesis of stereodefined 4-benzylidene-(or alkenylidene)-pyrrolidines from simple, readily available starting materials is described. This one-pot process is initiated by a conjugate addition of a propargylamine to a gem-diactivated olefin subsequently followed by a carbopalladat