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Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome

✍ Scribed by Ahsan M. Kaimul; Hajime Nakamura; Hiroshi Masutani; Junji Yodoi

Book ID
113630359
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
969 KB
Volume
43
Category
Article
ISSN
0891-5849

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Thioredoxin and thioredoxin binding prot
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## Abstract Thioredoxin (TRX) is a 12‐kDa protein with redox‐active dithiol in the active site ‐Cys‐Gly‐Pro‐Cys‐ and constitutes a major thiol reducing system. TRX protects cells from stress‐induced damage through antioxidative, antiapoptotic, and anti‐inflammatory effect. In animal models, thioace