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Redox Regulation by Thioredoxin and Thioredoxin-Binding Proteins

✍ Scribed by Akira Nishiyama; Hiroshi Masutani; Hajime Nakamura; Yumiko Nishinaka; Junji Yodoi


Book ID
111741419
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
300 KB
Volume
52
Category
Article
ISSN
1521-6543

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## Abstract Thioredoxin (TRX) is a 12‐kDa protein with redox‐active dithiol in the active site ‐Cys‐Gly‐Pro‐Cys‐ and constitutes a major thiol reducing system. TRX protects cells from stress‐induced damage through antioxidative, antiapoptotic, and anti‐inflammatory effect. In animal models, thioace

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