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Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities

โœ Scribed by Asal Fallah-Tafti; Alireza Foroumadi; Rakesh Tiwari; Amir Nasrolahi Shirazi; David G. Hangauer; Yahao Bu; Tahmineh Akbarzadeh; Keykavous Parang; Abbas Shafiee

Book ID
113583078
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
453 KB
Volume
46
Category
Article
ISSN
0223-5234

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## Abstract An ecofriendly and economical method for the synthesis of 3โ€substituted indoles (IV) (18 examples) via oneโ€pot threeโ€component coupling reaction of various benzaldehydes, Nโ€methylaniline, and indoles using Yb(OTf)~3~โ€SiO~2~ as catalyst is presented.