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Thiadiazolyl Quinazolones as Potential Antiviral and Antihypertensive Agents.

✍ Scribed by V. K. Pandey; Sarah Tusi; Zehra Tusi; R. Raghubir; M. Dixit; M. N. Joshi; S. K. Bajpai

Publisher
John Wiley and Sons
Year
2004
Weight
98 KB
Volume
35
Category
Article
ISSN
0931-7597

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Cyclic methyldopa analogs as potential a
Cyclic methyldopa analogs as potential antihypertensive and antineoplastic agents
✍ J. H. Burckhalter; GΓΌnter Schmied πŸ“‚ Article πŸ“… 1966 πŸ› John Wiley and Sons 🌐 English βš– 261 KB

Three cyclic methyldopa analogs ( I I I a , 6, and c) were synthesized by hydrolysis of the appropriate spirohydantoins (V), which were obtained through the Bucherer synthesis. Amino acids ( I I I a and b ) and hydantoins (Va and c) were inactive against experimental tumors. The 5 hydantoins tested