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TheTlaregion of the mouse: Identification of a new serologically defined locus,Qa-2

โœ Scribed by Lorraine Flaherty


Publisher
Springer-Verlag
Year
1976
Tongue
English
Weight
366 KB
Volume
3
Category
Article
ISSN
0093-7711

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A comprehensive analysis of human alloimmune cytotoxic T lymphocytes (CTLs) specific for the HLA-A2 antigen identified 11% of HLA-A2 positive cells as outliers. In total, 11 unrelated serologically indistinguishable, but distinguishable by cell-mediated lympholysis (CML) HLA-A2 positive outlier cell

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Human alloimmune cytotoxic T cells, sensitized selectively against the HLA-A2 antigen, were tested on a panel of selected target cells. Five HLA-A2 positive outlier cells could be identified. These outlier cells were only weakly lysed by HLA-A2 specific CTLs, although they were serologically indisti