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Thermodynamics of Fab−ssDNA Interactions: Contribution of Heavy Chain Complementarity Determining Region 3 †

✍ Scribed by Komissarov, Andrey A.; Deutscher, Susan L.

Book ID
127216387
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
73 KB
Volume
38
Category
Article
ISSN
0006-2960

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## Abstract The antigen binding site of an antibody is made up of residues residing in six hypervariable loops of the heavy and light chains. In most cases several or all of these loops are required for the establishment of the antigen‐binding surface. Five of these loops display a limited diversit